Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response

In clinical trials, metronomic cyclophosphamide (CPA) is increasingly being combined with vaccines to reduce tumor-induced immune suppression. Previous strategies to modulate the immune system during vaccination have involved continuous administration of low dose chemotherapy, studies that have pose...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Weir, Genevieve M, Hrytsenko, Olga, Stanford, Marianne M, Berinstein, Neil L, Karkada, Mohan, Liwski, Robert S, Mansour, Marc
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368141/
https://ncbi.nlm.nih.gov/pubmed/25960932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.953407
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