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Combination of poly I:C and Pam3CSK4 enhances activation of B cells in vitro and boosts antibody responses to protein vaccines in vivo

Vaccines that can rapidly induce strong and robust antibody-mediated immunity could improve protection from certain infectious diseases for which current vaccine formulations are inefficient. For indications such as anthrax and influenza, antibody production in vivo is a correlate of efficacy. Toll-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Weir, Genevieve M., Karkada, Mohan, Hoskin, David, Stanford, Marianne M., MacDonald, Lisa, Mansour, Marc, Liwski, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491120/
https://ncbi.nlm.nih.gov/pubmed/28662082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180073
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