Functional Differences Between IgM and IgD Signaling in Chronic Lymphocytic Leukemia

B-cell receptor (BCR) signaling is a central pathogenetic pathway in chronic lymphocytic leukemia (CLL). Most CLL cells express BCRs of IgM and IgD isotypes, but the contribution of these isotypes to functional responses remains incompletely defined. We therefore investigated differences between IgM...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hacken, Elisa ten, Sivina, Mariela, Kim, Ekaterina, O’Brien, Susan, Wierda, William G., Ferrajoli, Alessandra, Estrov, Zeev, Keating, Michael J., Oellerich, Thomas, Scielzo, Cristina, Ghia, Paolo, Caligaris-Cappio, Federico, Burger, Jan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010921/
https://ncbi.nlm.nih.gov/pubmed/27534555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600915
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