Functional Differences Between IgM and IgD Signaling in Chronic Lymphocytic Leukemia

B-cell receptor (BCR) signaling is a central pathogenetic pathway in chronic lymphocytic leukemia (CLL). Most CLL cells express BCRs of IgM and IgD isotypes, but the contribution of these isotypes to functional responses remains incompletely defined. We therefore investigated differences between IgM...

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Publié dans:J Immunol
Auteurs principaux: Hacken, Elisa ten, Sivina, Mariela, Kim, Ekaterina, O’Brien, Susan, Wierda, William G., Ferrajoli, Alessandra, Estrov, Zeev, Keating, Michael J., Oellerich, Thomas, Scielzo, Cristina, Ghia, Paolo, Caligaris-Cappio, Federico, Burger, Jan A.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010921/
https://ncbi.nlm.nih.gov/pubmed/27534555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600915
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