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Somatic engineering of oncogenic chromosomal rearrangements: a perspective

The ability to engineer specific mutations in mice has proven essential to advancing our understanding of the molecular basis of cancer. Chromosomal rearrangements, a common and clinically relevant class of cancer-causing mutations, have however remained difficult to faithfully recapitulate in vivo....

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Udgivet i:Cancer Res
Main Authors: Maddalo, Danilo, Ventura, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010508/
https://ncbi.nlm.nih.gov/pubmed/27520450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0726
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