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SEMMs: Somatically Engineered Mouse Models. A New Tool for In Vivo Disease Modeling for Basic and Translational Research

Most experimental oncology therapies fail during clinical development despite years of preclinical testing rationalizing their use. This begs the question of whether the current preclinical models used for evaluating oncology therapies adequately capture patient heterogeneity and response to therapy...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Lima, Anthony, Maddalo, Danilo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103029/
https://ncbi.nlm.nih.gov/pubmed/33968774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.667189
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