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Quality Over Quantity: Optimizing Co-translational Protein Folding With Non-“Optimal” Synonymous Codons
Protein folding occurs on a time scale similar to peptide bond formation by the ribosome, which has long sparked speculation that altering translation rate could alter the folding mechanism or even the final folded structure of a protein in vivo. Recent results have provided strong support for this...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Curr Opin Struct Biol |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010456/ https://ncbi.nlm.nih.gov/pubmed/27318814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.002 |
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