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Insight into G-quadruplex-hemin DNAzyme/RNAzyme: adjacent adenine as the intramolecular species for remarkable enhancement of enzymatic activity

G-quadruplex (G4) with stacked G-tetrads structure is able to bind hemin (iron (III)-protoporphyrin IX) to form a unique type of DNAzyme/RNAzyme with peroxidase-mimicking activity, which has been widely employed in multidisciplinary fields. However, its further applications are hampered by its relat...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Li, Wang, Li, Yong, Liu, Zhuoliang, Lin, Bin, Yi, Haibo, Xu, Feng, Nie, Zhou, Yao, Shouzhuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009756/
https://ncbi.nlm.nih.gov/pubmed/27422869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw634
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