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The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties

While many protein enzymes exert their functions through multimerization, which improves both selectivity and activity, this has not yet been demonstrated for other naturally occurring catalysts. Here, we report a multimerization effect applied to catalytic DNAs (or DNAzymes) and demonstrate that th...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Cheng, Yu, Cheng, Mingpan, Hao, Jingya, Jia, Guoqing, Monchaud, David, Li, Can
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163442/
https://ncbi.nlm.nih.gov/pubmed/34123138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02907f
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