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The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties

While many protein enzymes exert their functions through multimerization, which improves both selectivity and activity, this has not yet been demonstrated for other naturally occurring catalysts. Here, we report a multimerization effect applied to catalytic DNAs (or DNAzymes) and demonstrate that th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Cheng, Yu, Cheng, Mingpan, Hao, Jingya, Jia, Guoqing, Monchaud, David, Li, Can
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society of Chemistry 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163442/
https://ncbi.nlm.nih.gov/pubmed/34123138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02907f
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