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Site-Specific and Trigger-Activated Modification of Proteins by Means of Catalytic Hemin/G-quadruplex DNAzyme Nanostructures

[Image: see text] Catalytic nanostructures have the potency to mimic enzymatic features. In this paper, we show that the complex between hemin and G-quadruplex DNA efficiently catalyzes the modification of proteins with N-methyl luminol derivatives. Final conversions are reached within 15–30 min, an...

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Publicat a:Bioconjug Chem
Autors principals: Keijzer, Jordi F., Albada, Bauke
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581286/
https://ncbi.nlm.nih.gov/pubmed/32909740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00422
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