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Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preference

Homing endonucleases are sequence-tolerant DNA endonucleases that act as mobile genetic elements. The ability of homing endonucleases to cleave substrates with multiple nucleotide substitutions suggests a high degree of adaptability in that changing or modulating cleavage preference would require re...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Roy, Alexander C., Wilson, Geoffrey G., Edgell, David R.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009752/
https://ncbi.nlm.nih.gov/pubmed/27387281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw614
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