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Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine

DNA damage can significantly modulate expression of the affected genes either by direct structural interference with transcription components or as a collateral outcome of cellular repair attempts. Thus, DNA glycosylases of the base excision repair (BER) pathway have been implicated in negative tran...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Allgayer, Julia, Kitsera, Nataliya, Bartelt, Solveig, Epe, Bernd, Khobta, Andriy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009734/
https://ncbi.nlm.nih.gov/pubmed/27220469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw473
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