The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding

Chemical exposure of cells may damage biomolecules, cellular structures, and organelles thereby jeopardizing cellular homeostasis. A multitude of defense mechanisms have evolved that can recognize specific types of damaged molecules and will initiate distinct cellular programs aiming to remove the d...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Hendriks, Giel, Derr, Remco S., Misovic, Branislav, Morolli, Bruno, Calléja, Fabienne M. G. R., Vrieling, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Expanded ToxTracker Assay for Genotoxicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009621/
https://ncbi.nlm.nih.gov/pubmed/26719371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv323
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