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Genotoxic and mutagenic properties of Ni and NiO nanoparticles investigated by comet assay, γ‐H2AX staining, Hprt mutation assay and ToxTracker reporter cell lines

Nickel (Ni) compounds are classified as carcinogenic to humans but the underlying mechanisms are still poorly understood. Furthermore, effects related to nanoparticles (NPs) of Ni have not been fully elucidated. The aim of this study was to investigate genotoxicity and mutagenicity of Ni and NiO NPs...

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Détails bibliographiques
Publié dans:Environ Mol Mutagen
Auteurs principaux: Åkerlund, Emma, Cappellini, Francesca, Di Bucchianico, Sebastiano, Islam, Shafiqul, Skoglund, Sara, Derr, Remco, Odnevall Wallinder, Inger, Hendriks, Giel, Karlsson, Hanna L., Johnson, G.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888189/
https://ncbi.nlm.nih.gov/pubmed/29243303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22163
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