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The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding

Chemical exposure of cells may damage biomolecules, cellular structures, and organelles thereby jeopardizing cellular homeostasis. A multitude of defense mechanisms have evolved that can recognize specific types of damaged molecules and will initiate distinct cellular programs aiming to remove the d...

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Publicat a:Toxicol Sci
Autors principals: Hendriks, Giel, Derr, Remco S., Misovic, Branislav, Morolli, Bruno, Calléja, Fabienne M. G. R., Vrieling, Harry
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009621/
https://ncbi.nlm.nih.gov/pubmed/26719371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv323
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