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Assessment of ToxCast Phase II for Mitochondrial Liabilities Using a High-Throughput Respirometric Assay
Previous high-throughput screens to identify mitochondrial toxicants used immortalized cell lines and focused on changes in mitochondrial membrane potential, which may not be sufficient and do not identify different types of mitochondrial dysfunction. Primary cultures of renal proximal tubule cells...
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| Publicado en: | Toxicol Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009421/ https://ncbi.nlm.nih.gov/pubmed/25926417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv085 |
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