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Assessment of ToxCast Phase II for Mitochondrial Liabilities Using a High-Throughput Respirometric Assay

Previous high-throughput screens to identify mitochondrial toxicants used immortalized cell lines and focused on changes in mitochondrial membrane potential, which may not be sufficient and do not identify different types of mitochondrial dysfunction. Primary cultures of renal proximal tubule cells...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxicol Sci
Päätekijät: Wills, Lauren P., Beeson, Gyda C., Hoover, Douglas B., Schnellmann, Rick G., Beeson, Craig C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009421/
https://ncbi.nlm.nih.gov/pubmed/25926417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv085
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