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High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury
Many environmental chemicals and drugs negatively affect human health through deleterious effects on mitochondrial function. Currently there is no chemical library of mitochondrial toxicants, and no reliable methods for predicting mitochondrial toxicity. We hypothesized that discrete toxicophores de...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987703/ https://ncbi.nlm.nih.gov/pubmed/23811330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.06.014 |
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