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A high throughput respirometric assay for mitochondrial biogenesis and toxicity

Mitochondria are a common target of toxicity for drugs and other chemicals, and results in decreased aerobic metabolism and cell death. In contrast, mitochondrial biogenesis restores cell vitality and there is a need for new agents to induce biogenesis. Current cell-based models of mitochondrial bio...

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Autores principales: Beeson, Craig C., Beeson, Gyda C., Schnellmann, Rick G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900494/
https://ncbi.nlm.nih.gov/pubmed/20465991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.04.040
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