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Structure and Glycan Binding of a New Cyanovirin-N Homolog

The HIV-1 envelope glycoprotein gp120 is heavily glycosylated and bears numerous high mannose sugars. These sugars can serve as targets for HIV-inactivating compounds, such as antibodies and lectins, which bind to the glycans and interfere with viral entry into the target cell. We determined the 1.6...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Matei, Elena, Basu, Rohan, Furey, William, Shi, Jiong, Calnan, Conor, Aiken, Christopher, Gronenborn, Angela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009269/
https://ncbi.nlm.nih.gov/pubmed/27402833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740415
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