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Solution and crystal structures of a sugar binding site mutant of Cyanovirin-N: no evidence of domain-swapping
The cyanobacterial lectin Cyanovirin-N (CV-N) exhibits antiviral activity against HIV at a low nanomolar concentration by interacting with high-mannose oligosaccharides on the virus surface envelope glycoprotein gp120. Atomic structures of wild-type CV-N revealed a monomer in solution and a domain-s...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637156/ https://ncbi.nlm.nih.gov/pubmed/18682220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.05.011 |
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