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Structure and Glycan Binding of a New Cyanovirin-N Homolog

The HIV-1 envelope glycoprotein gp120 is heavily glycosylated and bears numerous high mannose sugars. These sugars can serve as targets for HIV-inactivating compounds, such as antibodies and lectins, which bind to the glycans and interfere with viral entry into the target cell. We determined the 1.6...

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Vydáno v:J Biol Chem
Hlavní autoři: Matei, Elena, Basu, Rohan, Furey, William, Shi, Jiong, Calnan, Conor, Aiken, Christopher, Gronenborn, Angela M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009269/
https://ncbi.nlm.nih.gov/pubmed/27402833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740415
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