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Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells

O-GlcNAcylation is a dynamic post-translational modification consisting of the addition of a single N-acetylglucosamine sugar to serine and threonine residues in proteins by the enzyme O-linked β-N-acetylglucosamine transferase (OGT), whereas the enzyme O-GlcNAcase (OGA) removes the modification. In...

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Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: de Queiroz, Rafaela Muniz, Madan, Rashna, Chien, Jeremy, Dias, Wagner Barbosa, Slawson, Chad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009264/
https://ncbi.nlm.nih.gov/pubmed/27402830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734533
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