O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the (A)γ-Globin Promoter

One mode of γ-globin gene silencing involves a GATA-1·FOG-1·Mi2β repressor complex that binds to the −566 GATA site relative to the (A)γ-globin gene cap site. However, the mechanism of how this repressor complex is assembled at the −566 GATA site is unknown. In this study, we demonstrate that the O-...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Zhang, Zhen, Costa, Flávia C., Tan, Ee Phie, Bushue, Nathan, DiTacchio, Luciano, Costello, Catherine E., McComb, Mark E., Whelan, Stephen A., Peterson, Kenneth R., Slawson, Chad
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957047/
https://ncbi.nlm.nih.gov/pubmed/27231347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721928
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