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Reversal of Ethanol-induced Intoxication by a Novel Modulator of Gβγ Protein Potentiation of the Glycine Receptor

The acute intoxicating effects of ethanol in the central nervous system result from the modulation of several molecular targets. It is widely accepted that ethanol enhances the activity of the glycine receptor (GlyR), thus enhancing inhibitory neurotransmission, leading to motor effects, sedation, a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: San Martin, Loreto, Cerda, Fabian, Jin, Chunyang, Jimenez, Veronica, Yevenes, Gonzalo E., Hernandez, Tania, Nova, Daniela, Fuentealba, Jorge, Aguayo, Luis G., Guzman, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009253/
https://ncbi.nlm.nih.gov/pubmed/27402845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740555
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