SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes

Recruitment of the deubiquitinase CYLD to signaling complexes is mediated by its interaction with HOIP, the catalytically active component of the linear ubiquitin chain assembly complex (LUBAC). Here, we identify SPATA2 as a constitutive direct binding partner of HOIP that bridges the interaction be...

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Vydáno v:Cell Rep
Hlavní autoři: Kupka, Sebastian, De Miguel, Diego, Draber, Peter, Martino, Luigi, Surinova, Silvia, Rittinger, Katrin, Walczak, Henning
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009064/
https://ncbi.nlm.nih.gov/pubmed/27545878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.086
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