Statin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner

Statins are widely prescribed to lower plasma low-density lipoprotein (LDL) cholesterol levels. They also modestly reduce plasma triglyceride (TG), an independent cardiovascular disease risk factor, in most people. The mechanism and inter-individual variability of TG statin response is poorly unders...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmacogenomics J
Prif Awduron: Theusch, E, Kim, K, Stevens, K, Smith, J D, Chen, Y -D I, Rotter, J I, Nickerson, D A, Medina, M W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008997/
https://ncbi.nlm.nih.gov/pubmed/26927283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2016.12
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