Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

Variation in the expression level and activity of genes involved in drug disposition and action (‘pharmacogenes') can affect drug response and toxicity, especially when in tissues of pharmacological importance. Previous studies have relied primarily on microarrays to understand gene expression...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Chhibber, A, French, C E, Yee, S W, Gamazon, E R, Theusch, E, Qin, X, Webb, A, Papp, A C, Wang, A, Simmons, C Q, Konkashbaev, A, Chaudhry, A S, Mitchel, K, Stryke, D, Ferrin, T E, Weiss, S T, Kroetz, D L, Sadee, W, Nickerson, D A, Krauss, R M, George, A L, Schuetz, E G, Medina, M W, Cox, N J, Scherer, S E, Giacomini, K M, Brenner, S E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980276/
https://ncbi.nlm.nih.gov/pubmed/26856248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.93
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