Blockage of autophagy pathway enhances Salmonella tumor-targeting

Previous studies have shown that strains of Salmonella typhimurium specifically target tumors in mouse models of cancer. In this study, we report that tumor-targeting Salmonella typhimurium A1-R (A1-R) or VNP20009 induced autophagy in human cancer cells, which serves as a defense response. Functiona...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Binghong, Jiang, Yanan, Dong, Tiangeng, Zhao, Ming, Wu, Jianfu, Li, Lihui, Chu, Yiwei, She, Shangyang, Zhao, Hu, Hoffman, Robert M., Jia, Lijun
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008408/
https://ncbi.nlm.nih.gov/pubmed/27013582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8251
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