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Consequences of the selective blockage of chaperone-mediated autophagy
Chaperone-mediated autophagy (CMA) is a selective pathway for the degradation of cytosolic proteins in lysosomes. CMA declines with age because of a decrease in the levels of lysosome-associated membrane protein (LAMP) type 2A, a lysosomal receptor for this pathway. We have selectively blocked the e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458654/ https://ncbi.nlm.nih.gov/pubmed/16585521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507436103 |
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