High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients

Compelling epidemiological evidences indicate a significant association between leukocyte mitochondrial DNA (mtDNA) content and incidence risk of several malignancies, including hepatocellular carcinoma (HCC). However, whether leukocyte mtDNA content affect prognosis of HCC patients and underlying m...

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Publicado en:Oncotarget
Autores principales: He, Xianli, Qu, Falin, Zhou, Feng, Zhou, Xingchun, Chen, Yibing, Guo, Xu, Li, Jibin, Huang, Qichao, Yang, Yefa, Lyu, Zhuomin, Zhang, Hongxin, Xing, Jinliang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008404/
https://ncbi.nlm.nih.gov/pubmed/26985767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8071
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