High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients

Compelling epidemiological evidences indicate a significant association between leukocyte mitochondrial DNA (mtDNA) content and incidence risk of several malignancies, including hepatocellular carcinoma (HCC). However, whether leukocyte mtDNA content affect prognosis of HCC patients and underlying m...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: He, Xianli, Qu, Falin, Zhou, Feng, Zhou, Xingchun, Chen, Yibing, Guo, Xu, Li, Jibin, Huang, Qichao, Yang, Yefa, Lyu, Zhuomin, Zhang, Hongxin, Xing, Jinliang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008404/
https://ncbi.nlm.nih.gov/pubmed/26985767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8071
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