Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer

Colorectal cancer is one of the leading causes of cancer death worldwide. According to global genomic status, colorectal cancer can be classified into two main types: microsatellite-stable and microsatellite-instable tumors. Moreover, the two subtypes also exhibit different responses to chemotherape...

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Vydáno v:Signal Transduct Target Ther
Hlavní autoři: Sun, Xiacheng, Zhan, Lei, Chen, Yibing, Wang, Gang, He, Linjie, Wang, Qian, Zhou, Feng, Yang, Fang, Wu, Jin, Wu, Yousheng, Xing, Jinliang, He, Xianli, Huang, Qichao
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878831/
https://ncbi.nlm.nih.gov/pubmed/29610678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-018-0011-z
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