High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients

Compelling epidemiological evidences indicate a significant association between leukocyte mitochondrial DNA (mtDNA) content and incidence risk of several malignancies, including hepatocellular carcinoma (HCC). However, whether leukocyte mtDNA content affect prognosis of HCC patients and underlying m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: He, Xianli, Qu, Falin, Zhou, Feng, Zhou, Xingchun, Chen, Yibing, Guo, Xu, Li, Jibin, Huang, Qichao, Yang, Yefa, Lyu, Zhuomin, Zhang, Hongxin, Xing, Jinliang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008404/
https://ncbi.nlm.nih.gov/pubmed/26985767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8071
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