High leukocyte mtDNA content contributes to poor prognosis through ROS-mediated immunosuppression in hepatocellular carcinoma patients

Compelling epidemiological evidences indicate a significant association between leukocyte mitochondrial DNA (mtDNA) content and incidence risk of several malignancies, including hepatocellular carcinoma (HCC). However, whether leukocyte mtDNA content affect prognosis of HCC patients and underlying m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Xianli, Qu, Falin, Zhou, Feng, Zhou, Xingchun, Chen, Yibing, Guo, Xu, Li, Jibin, Huang, Qichao, Yang, Yefa, Lyu, Zhuomin, Zhang, Hongxin, Xing, Jinliang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008404/
https://ncbi.nlm.nih.gov/pubmed/26985767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8071
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