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Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Osteosarcoma is the most common primary bone malignancy affecting children and adolescents. Although several genetic predisposing conditions have been associated with osteosarcoma, our understanding of its pathobiology is rather limited. Here we show that, first, an imprinting defect at human 14q32-...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Shu, Jingmin, Li, Lihua, Sarver, Anne E., Pope, Emily A., Varshney, Jyotika, Thayanithy, Venugopal, Spector, Logan, Largaespada, David A., Steer, Clifford J., Subramanian, Subbaya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008286/
https://ncbi.nlm.nih.gov/pubmed/26802029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6965
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