Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma

Osteosarcoma is the most common primary bone malignancy affecting children and adolescents. Although several genetic predisposing conditions have been associated with osteosarcoma, our understanding of its pathobiology is rather limited. Here we show that, first, an imprinting defect at human 14q32-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shu, Jingmin, Li, Lihua, Sarver, Anne E., Pope, Emily A., Varshney, Jyotika, Thayanithy, Venugopal, Spector, Logan, Largaespada, David A., Steer, Clifford J., Subramanian, Subbaya
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008286/
https://ncbi.nlm.nih.gov/pubmed/26802029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6965
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