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Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance
Quinolone antimicrobials are widely used in clinical medicine and are the only current class of agents that directly inhibit bacterial DNA synthesis. Quinolones dually target DNA gyrase and topoisomerase IV binding to specific domains and conformations so as to block DNA strand passage catalysis and...
Na minha lista:
| Foilsithe in: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Cold Spring Harbor Laboratory Press
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008060/ https://ncbi.nlm.nih.gov/pubmed/27449972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025320 |
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