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Emerging Mechanisms of Fluoroquinolone Resistance

Broad use of fluoroquinolones has been followed by emergence of resistance, which has been due mainly to chromosomal mutations in genes encoding the subunits of the drugs' target enzymes, DNA gyrase and topoisomerase IV, and in genes that affect the expression of diffusion channels in the outer...

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Détails bibliographiques
Auteur principal: David C. Hooper
Format: Artigo
Langue:Inglês
Publié: Centers for Disease Control and Prevention 2001-04-01
Collection:Emerging Infectious Diseases
Sujets:
Accès en ligne:https://wwwnc.cdc.gov/eid/article/7/2/70-0337_article
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