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Model systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicity
Chaperones and co-chaperones enable protein folding and degradation, safeguarding the proteome against proteotoxic stress. Chaperones display dynamic responses to exogenous and endogenous stressors and thus constitute a key component of the proteostasis network (PN), an intricately regulated network...
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| Udgivet i: | Dis Model Mech |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007983/ https://ncbi.nlm.nih.gov/pubmed/27491084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024703 |
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