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Chaperone networks: Tipping the balance in protein folding diseases

Adult-onset neurodegeneration and other protein conformational diseases are associated with the appearance, persistence, and accumulation of misfolded and aggregation prone proteins. To protect the proteome from long-term damage, the cell expresses a highly integrated protein homeostasis (proteostas...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Voisine, Cindy, Pedersen, Jesper Søndergaard, Morimoto, Richard I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429345/
https://ncbi.nlm.nih.gov/pubmed/20472062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.05.007
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