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Chaperone networks: Tipping the balance in protein folding diseases
Adult-onset neurodegeneration and other protein conformational diseases are associated with the appearance, persistence, and accumulation of misfolded and aggregation prone proteins. To protect the proteome from long-term damage, the cell expresses a highly integrated protein homeostasis (proteostas...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429345/ https://ncbi.nlm.nih.gov/pubmed/20472062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.05.007 |
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