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Chaperoning osteogenesis: new protein-folding-disease paradigms

Recent discoveries of severe bone disorders in patients with deficiencies in several endoplasmic reticulum chaperones are reshaping the discussion of type I collagen folding and related diseases. Type I collagen is the most abundant protein in all vertebrates and a crucial structural molecule for bo...

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Main Authors: Makareeva, Elena, Aviles, Nydea A., Leikin, Sergey
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057343/
https://ncbi.nlm.nih.gov/pubmed/21183349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.11.007
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