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Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

The long-term health of the cell is inextricably linked to protein quality control. Under optimal conditions this is accomplished by protein homeostasis, a highly complex network of molecular interactions that balances protein biosynthesis, folding, translocation, assembly/disassembly, and clearance...

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Detalhes bibliográficos
Autor principal: Morimoto, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732416/
https://ncbi.nlm.nih.gov/pubmed/18519635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1657108
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