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How the nucleus copes with proteotoxic stress
The proper folding of proteins is continuously challenged by intrinsic and extrinsic stresses, and the accumulation of toxic misfolded proteins is associated with many human diseases. Eukaryotic cells have evolved a complex network of protein quality control pathways to protect the proteome, and the...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207067/ https://ncbi.nlm.nih.gov/pubmed/24845679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.03.033 |
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