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Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112

The histone acetyltransferase (HAT) enzymes p300 and CBP are closely related paralogs that serve as transcriptional coactivators and have been found to be dysregulated in cancer and other diseases. p300/CBP is a multidomain protein and possesses a highly conserved bromodomain that has been shown to...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Zucconi, Beth E., Luef, Birgit, Xu, Wei, Henry, Ryan A., Nodelman, Ilana M., Bowman, Gregory D., Andrews, Andrew J., Cole, Philip A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007619/
https://ncbi.nlm.nih.gov/pubmed/27332697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00480
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