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Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded. However, the responsible quality control (QC) mechanisms remain poorly characte...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Sung, Min-Kyung, Reitsma, Justin M., Sweredoski, Michael J., Hess, Sonja, Deshaies, Raymond J.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007085/
https://ncbi.nlm.nih.gov/pubmed/27385339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-05-0290
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