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Ribosomal proteins produced in excess are degraded by the ubiquitin–proteasome system

Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded. However, the responsible quality control (QC) mechanisms remain poorly characte...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Sung, Min-Kyung, Reitsma, Justin M., Sweredoski, Michael J., Hess, Sonja, Deshaies, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007085/
https://ncbi.nlm.nih.gov/pubmed/27385339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-05-0290
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