Brown-like adipose progenitors derived from human induced pluripotent stem cells: Identification of critical pathways governing their adipogenic capacity

Human induced pluripotent stem cells (hiPSCs) show great promise for obesity treatment as they represent an unlimited source of brown/brite adipose progenitors (BAPs). However, hiPSC-BAPs display a low adipogenic capacity compared to adult-BAPs when maintained in a traditional adipogenic cocktail. T...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hafner, Anne-Laure, Contet, Julian, Ravaud, Christophe, Yao, Xi, Villageois, Phi, Suknuntha, Kran, Annab, Karima, Peraldi, Pascal, Binetruy, Bernard, Slukvin, Igor I., Ladoux, Annie, Dani, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006163/
https://ncbi.nlm.nih.gov/pubmed/27577850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32490
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