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The Primary Cilium of Adipose Progenitors Is Necessary for Their Differentiation into Cancer-Associated Fibroblasts that Promote Migration of Breast Cancer Cells In Vitro

Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shaped organelle, controls several aspects of APs’ bio...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Peraldi, Pascal, Ladoux, Annie, Giorgetti-Peraldi, Sophie, Dani, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601294/
https://ncbi.nlm.nih.gov/pubmed/33049976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102251
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