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Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors

Maintenance of the adipose tissue requires a proper balance between self-renewal and differentiation of adipose progenitors (AP). Any deregulation leads either to fat overexpansion and obesity or fat loss and consequent lipodystrophies. Depending on the fat pad location, APs and adipocytes are heter...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ravaud, Christophe, Paré, Martin, Azoulay, Stéphane, Dani, Christian, Ladoux, Annie
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462747/
https://ncbi.nlm.nih.gov/pubmed/28592814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02807-9
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