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The Primary Cilium of Adipose Progenitors Is Necessary for Their Differentiation into Cancer-Associated Fibroblasts that Promote Migration of Breast Cancer Cells In Vitro

Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shaped organelle, controls several aspects of APs’ bio...

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Detalles Bibliográficos
Publicado en:Cells
Main Authors: Peraldi, Pascal, Ladoux, Annie, Giorgetti-Peraldi, Sophie, Dani, Christian
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601294/
https://ncbi.nlm.nih.gov/pubmed/33049976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102251
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