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The Primary Cilium of Adipose Progenitors Is Necessary for Their Differentiation into Cancer-Associated Fibroblasts that Promote Migration of Breast Cancer Cells In Vitro

Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shaped organelle, controls several aspects of APs’ bio...

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Vydáno v:Cells
Hlavní autoři: Peraldi, Pascal, Ladoux, Annie, Giorgetti-Peraldi, Sophie, Dani, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601294/
https://ncbi.nlm.nih.gov/pubmed/33049976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102251
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