Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death.

Very little is known regarding the effects of ionizing radiation on cytoplasmic signal transduction pathways. Here, we show that ionizing radiation induces enhanced tyrosine phosphorylation of multiple substrates in human B-lymphocyte precursors. This response to ionizing radiation was also observed...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Uckun, F M, Tuel-Ahlgren, L, Song, C W, Waddick, K, Myers, D E, Kirihara, J, Ledbetter, J A, Schieven, G L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9005
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